Babesia microti and Babesia divergens are obligate intra-erythrocytic protozoans transmitted by tick vectors, causing flu-like symptoms as well as a malaria-like illness in humans. Both agents can be transmitted by blood donor units from asymptomatic donors and are found worldwide.
Our IFA slide antigens are all propagated in vitro using human type O erythrocytes to provide the cleanest and most sensitive reactivity possible. We are recommending a new screening format using a conjugate for both IgG and IgM at screening dilution (1:64) in order to detect all acute cases. High IgM titers are common in acute phase and it is safe practice to avoid prozone false-negative IgG in the screening phase. These kits are called BMT-120 and DVT-120 for "total antibody" and positive sera should be followed with IgG and IgM-specific titers for accurate staging.